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Results for "

Protein kinase B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AAK1 (2) Akt (5) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (7) Aurora Kinase (2) Bacterial (2) Bcr-Abl (1) Bradykinin Receptor (1) CaMK (1) CDK (8) COX (2) Cyclin G-associated Kinase (GAK) (2) EGFR (1) Endogenous Metabolite (3) ERK (1) Ferroptosis (2) FLT3 (1) GSK-3 (1) IRAK (1) JAK (1) LIM Kinase (LIMK) (3) MAP4K (1) MAPKAPK2 (MK2) (1) MEK (1) NF-κB (2) NO Synthase (1) Orthopoxvirus (3) Parasite (1) Phosphatase (1) PKC (3) PROTACs (4) Raf (2) ROCK (1) Salt-inducible Kinase (SIK) (3) STAT (3) TOPK (1) Topoisomerase (3) Trk Receptor (1) ULK (2) Wee1 (2)
By Research Areas:	Cancer (21) Cardiovascular Disease (2) Infection (6) Inflammation/Immunology (4) Neurological Disease (1)

By Targets:

AAK1 (2)

Akt (5)

Anaplastic lymphoma kinase (ALK) (1)

Apoptosis (7)

Aurora Kinase (2)

Bacterial (2)

Bcr-Abl (1)

Bradykinin Receptor (1)

CaMK (1)

CDK (8)

COX (2)

Cyclin G-associated Kinase (GAK) (2)

EGFR (1)

Endogenous Metabolite (3)

ERK (1)

Ferroptosis (2)

FLT3 (1)

GSK-3 (1)

IRAK (1)

JAK (1)

LIM Kinase (LIMK) (3)

MAP4K (1)

MAPKAPK2 (MK2) (1)

MEK (1)

NF-κB (2)

NO Synthase (1)

Orthopoxvirus (3)

Parasite (1)

Phosphatase (1)

PKC (3)

PROTACs (4)

Raf (2)

ROCK (1)

Salt-inducible Kinase (SIK) (3)

STAT (3)

TOPK (1)

Topoisomerase (3)

Trk Receptor (1)

ULK (2)

Wee1 (2)

By Research Areas:

Cancer (21)

Cardiovascular Disease (2)

Infection (6)

Inflammation/Immunology (4)

Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130517

Cdc7-IN-5	CDK	Cancer
Cdc7-IN-5 (compound I-B) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle .

HY-136219

Protein kinase affinity probe 1	Others	Others
Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3) .

HY-143882

MS5033

PROTACs Akt Cancer

MS5033 is a potent PROTAC-based AKT (protein kinase B) degrader, with a DC₅₀ of 430 nM in PC3 cells .
HY-151206

PknB-IN-2

Bacterial Infection

PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC₅₀ of 12.1 μM .
HY-143611

AKT-IN-8

Akt Cancer

AKT-IN-8 is a potent AKT inhibitor with IC₅₀s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively .

MS5033	PROTACs Akt	Cancer
MS5033 is a potent PROTAC-based *AKT (protein* kinase B)** degrader, with a DC₅₀ of 430 nM in PC3 cells .

PknB-IN-2	Bacterial	Infection
PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC₅₀ of 12.1 μM .

AKT-IN-8	Akt	Cancer
AKT-IN-8 is a potent AKT inhibitor with IC₅₀s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively .

HY-N0811

Anemarsaponin B	NO Synthase COX NF-κB MEK	Inflammation/Immunology
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect .

HY-142820

B-Raf IN 5	Raf	Cancer
B-Raf IN 5 (compound 3b) is a potent inhibitor of protein kinase *B-Raf* with an IC₅₀ of 2.0 nM. B-Raf IN 5 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease .

HY-142830

B-Raf IN 6	Raf	Cancer
B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase *B-Raf* with an IC₅₀ of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease .

HY-130515

Cdc7-IN-3	CDK	Cancer
Cdc7-IN-3 (compound I-A) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle .

HY-12467

OTS964 hydrochloride 5+ Cited Publications	TOPK CDK Apoptosis	Cancer
OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC₅₀ of 28 nM . OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a K_d of 40 nM .

HY-153011

ROCK-IN-5	ROCK ERK GSK-3	Cardiovascular Disease Neurological Disease
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research .

HY-N9561

Vanicoside B	CDK STAT	Cancer
Vanicoside B is a phenylpropanoyl sucrose derivative, can be isolated from the herb Persicaria dissitiflora. Vanicoside B targets *cyclin-dependent kinase* 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8*-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis* .

HY-137377

TAS-119	Aurora Kinase	Cancer
TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC₅₀ of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B (IC₅₀ of 95 nM). TAS-119 has potent antitumor activites .

HY-161351

STAT3/AKT-IN-1	Akt STAT Apoptosis	Cancer
STAT3/AKT-IN-1 is a dual inhibitor for the signal transducer and activator of transcription 3 (STAT3) and protein kinase B (AKT) signalling pathway, exhibits antitumor activity against gastric cancer and induces cell apoptosis in SGC-7901 cells .

HY-151204

PknB-IN-1	Bacterial	Infection Inflammation/Immunology
PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC₅₀=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL) .

HY-N3634

Corylifol C	Others	Cancer
Corylifol C is a potent **protein kinase inhibitor with IC₅₀** valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively .

HY-148063

DB0614	PROTACs AAK1 Aurora Kinase CaMK CDK Ferroptosis Salt-inducible Kinase (SIK) ULK Wee1 LIM Kinase (LIMK)	Others
DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK, LCK, LIMK2, MAP3KH, MAPK8, MAPK9, NEK9, PLK4, PTK2B, SIK2, STK17A, STK17B, ULK1, ULK3, and WEE1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-103292

[Phe8Ψ(CH-NH)Arg9]-Bradykinin	Bradykinin Receptor	Cardiovascular Disease
[Phe8Ψ(CH-NH)Arg9]-Bradykinin is a selective Bradykinin receptor B₂ agonist (not cleaved by protein kinase I/II). [Phe8Ψ(CH-NH)Arg9]-Bradykinin has potential for the research of hypertension .

HY-18299

Purvalanol B 1 Publications Verification NG 95	CDK Parasite	Infection Cancer
Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC₅₀s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC₅₀>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum .

HY-13502

Mitoxantrone Maximum Cited Publications 18 Publications Verification Mitozantrone; NSC 301739	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite	Infection Cancer
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity . Mitoxantrone also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

HY-13502A

Mitoxantrone dihydrochloride Maximum Cited Publications 18 Publications Verification Mitozantrone dihydrochloride; NSC 301739 dihydrochloride	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite	Infection Cancer
Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity . Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

HY-13502B

Mitoxantrone diacetate Mitozantrone diacetate; NSC 301739 diacetate	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite	Infection Cancer
Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity . Mitoxantrone diacetate also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

HY-139374

Zabedosertib 1 Publications Verification BAY 1834845	IRAK	Inflammation/Immunology
Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC₅₀ is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors . Zabedosertib exhibits anti-inflammatory property against IL-β, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation .

HY-148234

M4K2234	Anaplastic lymphoma kinase (ALK)	Cancer
M4K2234 (compound 26b) is an ALK2 inhibitor. M4K2234 inhibits ALK2 and ALK5 with IC₅₀s of 5 and 2144 nM, respectively. M4K2234 can be used as a chemical probe for ALK1 and ALK2 protein kinases. M4K2234 can be used for the research of cancer .

HY-100499

Tyrphostin AG 528 Tyrphostin B66; AG 528	EGFR	Cancer
Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC₅₀s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC₅₀s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for ErbB2 . Tyrphostin AG 528 is also an anticancer agent .

HY-144059

AKT-IN-9	Akt	Cancer
AKT-IN-9 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-9 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 1) .

HY-144060

AKT-IN-10	Akt	Cancer
AKT-IN-10 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-10 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 4) .

HY-148062

RSS0680	PROTACs CDK AAK1 Cyclin G-associated Kinase (GAK) Salt-inducible Kinase (SIK) LIM Kinase (LIMK) Wee1	Others
RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-148061

DB1113	PROTACs Bcr-Abl CDK Salt-inducible Kinase (SIK) Cyclin G-associated Kinase (GAK) MAP4K MAPKAPK2 (MK2) Ferroptosis ULK LIM Kinase (LIMK)	Others
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-50867

Lestaurtinib 3 Publications Verification CEP-701; KT-5555	JAK FLT3 Trk Receptor Apoptosis STAT	Cancer
Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the *TrkA/B/C* domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC₅₀s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor .

HY-108543

NSC 95397 4 Publications Verification	Phosphatase Apoptosis	Cancer
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (K_i=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC₅₀=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)) . NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway .

HY-N0632

Esculentoside A 2 Publications Verification	COX NF-κB	Inflammation/Immunology
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

Cat. No.	Product Name

HY-L008

JAK/STAT Compound Library	423 compounds
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane proteins that recognize specific cytokines, and is critical in blood formation and immune response. Canonical JAK/STAT signaling begins with the association of cytokines and their corresponding transmembrane receptors. Activated JAKs then phosphorylate latent STAT monomers, leading to dimerization, nuclear translocation, and DNA binding. In mammals, there are four JAKs (JAK1, JAK2, JAK3, TYK2) and seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). Since the JAK/STAT pathway plays a major role in many fundamental processes, such as apoptosis and inflammation, dysfunctional proteins in the pathway may lead to a number of diseases. For example, alterations in JAK/STAT signalling can result in cancer and diseases affecting the immune system, such as severe combined immunodeficiency disorder (SCID). MCE provides 423 compounds that can be used in the study of the JAK/STAT signaling pathway and related diseases.

JAK/STAT Compound Library

423 compounds

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane proteins that recognize specific cytokines, and is critical in blood formation and immune response. Canonical JAK/STAT signaling begins with the association of cytokines and their corresponding transmembrane receptors. Activated JAKs then phosphorylate latent STAT monomers, leading to dimerization, nuclear translocation, and DNA binding. In mammals, there are four JAKs (JAK1, JAK2, JAK3, TYK2) and seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). Since the JAK/STAT pathway plays a major role in many fundamental processes, such as apoptosis and inflammation, dysfunctional proteins in the pathway may lead to a number of diseases. For example, alterations in JAK/STAT signalling can result in cancer and diseases affecting the immune system, such as severe combined immunodeficiency disorder (SCID).

MCE provides 423 compounds that can be used in the study of the JAK/STAT signaling pathway and related diseases.

Cat. No.	Product Name	Target	Research Area

HY-103292

[Phe8Ψ(CH-NH)Arg9]-Bradykinin	Bradykinin Receptor	Cardiovascular Disease
[Phe8Ψ(CH-NH)Arg9]-Bradykinin is a selective Bradykinin receptor B₂ agonist (not cleaved by protein kinase I/II). [Phe8Ψ(CH-NH)Arg9]-Bradykinin has potential for the research of hypertension .

Mitoxantrone Maximum Cited Publications 18 Publications Verification Mitozantrone; NSC 301739	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields Cancer	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity . Mitoxantrone also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

Mitoxantrone dihydrochloride Maximum Cited Publications 18 Publications Verification Mitozantrone dihydrochloride; NSC 301739 dihydrochloride	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields Cancer	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite
Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity . Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

Anemarsaponin B	Structural Classification Liliaceae Classification of Application Fields Source classification Anemarrhena asphodeloides Bunge Plants Inflammation/Immunology Disease Research Fields Steroids	NO Synthase COX NF-κB MEK
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect .

Vanicoside B	Structural Classification Polygonaceae Source classification Phenols Polyphenols Plants Perilla ocimoides L.	CDK STAT
Vanicoside B is a phenylpropanoyl sucrose derivative, can be isolated from the herb Persicaria dissitiflora. Vanicoside B targets *cyclin-dependent kinase* 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8*-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis* .

Corylifol C	Structural Classification Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants	Others
Corylifol C is a potent **protein kinase inhibitor with IC₅₀** valueS of 8.7, 3.0, 2.1, 6.4, 4.5, 6.2, 2.3, 1.2, 5.1 μg/ml for ARK5, Aurora-A, Aurora-B, AXL, B-RAF-VE, CDK4/CycD1, TIE2, EGF-R, EPHB4, respectively .

Mitoxantrone diacetate Mitozantrone diacetate; NSC 301739 diacetate	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Endogenous metabolite Disease Research Fields Cancer	Topoisomerase PKC Orthopoxvirus Apoptosis Endogenous Metabolite
Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C (PKC) activity with an IC₅₀ of 8.5 μM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity . Mitoxantrone diacetate also has anti-orthopoxvirus activity with EC₅₀s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively .

Esculentoside A 2 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Phytolacca acinosa Roxb. Plants Inflammation/Immunology Disease Research Fields Phytolaccaceae	COX NF-κB
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

Species:	Human (62) Mouse (9) Rat (3) E.coli (2) Cynomolgus (1)
Tag:	His (38) SUMO (2) Tag Free (9) GST (27) Fc (9) Flag (1) B2M (1)
Source:	HEK293 (24) Sf9 insect cells (36) P. pastoris (3) E. coli (14)

Cat. No.	Compare	Product Name	Species	Source

HY-P702717

	PTK2B Protein, Human (sf9) PTK2B; PTK2B Protein tyrosine kinase 2 beta; FAK2, Protein tyrosine kinase 2 beta; Protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; Protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase; PKB; FAK2; FADK2	Human	Sf9 insect cells

HY-P702632

	AKT2 Protein, Human (Active, sf9, GST) AKT2; v-akt murine thymoma viral oncogene homolog 2; PKBB; PRKBB; PKBBETA; RAC-BETA; AKT2 kinase; rac Protein kinase beta; Murine thymoma viral (v-akt) homolog-2; EC 2.7.11.1; RAC-beta serine/threonine-Protein kinase; RAC-PK-beta; Protein kinase Akt-2; Protein kinase B, beta; PKB beta	Human	Sf9 insect cells

HY-P702631

	AKT1 Protein, Human (Active, sf9, GST) AKT1; v-akt murine thymoma viral oncogene homolog 1; RAC-alpha serine/threonine-Protein kinase; AKT; PKB; PRKBA; RAC; PKB alpha; RAC-PK-alpha; proto-oncogene c-Akt; Protein kinase B alpha; rac Protein kinase alpha; PKB-ALPHA; RAC-ALPHA; MGC99656	Human	Sf9 insect cells

HY-P701670

	DYRK1B Protein, Human (Sf9, GST) DYRK1B; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk Protein kinase	Human	Sf9 insect cells
	DYRK1B protein has dual serine/threonine and tyrosine kinase activities. DYRK1B Protein, Human (Sf9, GST) is the recombinant human-derived DYRK1B protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of DYRK1B Protein, Human (Sf9, GST) is 628 a.a., .

HY-P7897

	*Creatine kinase* B-type/CKB Protein, Human (His)** rHuCreatine kinase B-type/CKB , His; B-CK; CKB; Creatine kinase BB	Human	E. coli
	Creatine kinaseB-type/CKB Protein, Human (His) is the most abundant creatine kinase isoenzyme in purified brown adipocytes. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens.

HY-P701729

	WEE2 Protein, Human (Sf9, His, GST) WEE2; Wee1-like Protein kinase 2; Wee1-like Protein kinase 1B; Wee1B kinase	Human	Sf9 insect cells
	WEE2 protein is an oocyte-specific tyrosine kinase that plays an important role in meiosis during prophase I and metaphase II. It maintains meiotic arrest at the germinal vesicle (GV) stage by phosphorylating CDK1 at 'Tyr-15', inhibiting CDK1 activity and preventing reentry. WEE2 Protein, Human (Sf9, His, GST) is the recombinant human-derived WEE2 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of WEE2 Protein, Human (Sf9, His, GST) is 566 a.a., .

HY-P70040

	BLK Protein, Human (His) rHuTyrosine-Protein kinase Blk/BLK, His; Tyrosine-Protein kinase Blk; B Lymphocyte kinase; p55-Blk; BLK	Human	E. coli
	The BLK protein is a key non-receptor tyrosine kinase that is essential for B lymphocyte development and signal transduction. It regulates pro-B to pre-B transition, growth arrest, and apoptosis downstream of B cell receptors by binding and phosphorylating CD79A and CD79B. BLK Protein, Human (His) is the recombinant human-derived BLK protein, expressed by E. coli , with C-6*His labeled tag. The total length of BLK Protein, Human (His) is 504 a.a., with molecular weight of ~60.0 kDa.

HY-P701730

	P38β Protein, Human (Sf9) MAPK11; Mitogen-activated Protein kinase 11; MAP kinase 11; MAPK 11; Mitogen-activated Protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated Protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (Sf9) is the recombinant human-derived P38β protein, expressed by Sf9 insect cells , with tag free. The total length of P38β Protein, Human (Sf9) is 363 a.a., .

HY-P701731

	P38β Protein, Human (Sf9, GST) MAPK11; Mitogen-activated Protein kinase 11; MAP kinase 11; MAPK 11; Mitogen-activated Protein kinase p38 beta; MAP kinase p38 beta; p38b; Stress-activated Protein kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (Sf9, GST) is the recombinant human-derived P38β protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of P38β Protein, Human (Sf9, GST) is 363 a.a., .

HY-P71517

	*Hygromycin-B kinase/HPH Protein, E.coli (His-SUMO)* hphHygromycin-B 4-O-kinase; EC 2.7.1.163; APH(4); Hygromycin B phosphotransferase; Hygromycin-B kinase	E.coli	E. coli
	Hygromycin-B kinase/HPH Proteinas, an aminoglycoside phosphotransferase, phosphorylates and inactivates antibiotic substrates, including hygromycin and related compounds. This selective enzymatic activity highlights its specificity within the aminoglycoside class, regulating antibiotic function and potentially influencing microbial resistance mechanisms. Hygromycin-B kinase/HPH Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Hygromycin-B kinase/HPH protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Hygromycin-B kinase/HPH Protein, E.coli (His-SUMO) is 341 a.a., with molecular weight of ~54.0 kDa.

HY-P701790

	JNK3 Protein, Human MAPK10; Mitogen-activated Protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated Protein kinase 1b; SAPK1b; Stress-activated Protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human is the recombinant human-derived JNK3 protein, expressed by E. coli , with tag free. The total length of JNK3 Protein, Human is 423 a.a., .

HY-P701791

	JNK3 Protein, Human (His) MAPK10; Mitogen-activated Protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated Protein kinase 1b; SAPK1b; Stress-activated Protein kinase JNK3; c-Jun N-terminal kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human (His) is the recombinant human-derived JNK3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of JNK3 Protein, Human (His) is 423 a.a., .

HY-P701786

	IKKβ Protein, Human (Sf9, GST) IKBKβ; Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine Protein kinase IKBKB	Human	Sf9 insect cells
	IKKβ protein is a serine kinase that is critical in the NF-kappa-B signaling pathway and can respond to various stimuli such as cytokines or cellular stress. As part of the classical IKK complex, IKKβ activates NF-kappa-B through phosphorylation inhibitors, leading to its degradation and release of NF-kappa-B for gene transcription. IKKβ Protein, Human (Sf9, GST) is the recombinant human-derived IKKβ protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P700600

	*Hygromycin-B kinase/HPH Protein, E.coli (P. pastoris, His)* hphHygromycin-B 4-O-kinase; EC 2.7.1.163; APH(4); Hygromycin B phosphotransferase; Hygromycin-B kinase	E.coli	P. pastoris
	Hygromycin-B kinase/HPH Proteinas, an aminoglycoside phosphotransferase, phosphorylates and inactivates antibiotic substrates, including hygromycin and related compounds. This selective enzymatic activity highlights its specificity within the aminoglycoside class, regulating antibiotic function and potentially influencing microbial resistance mechanisms. Hygromycin-B kinase/HPH Protein, E.coli (P. pastoris, His) is the recombinant E. coli-derived Hygromycin-B kinase/HPH protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Hygromycin-B kinase/HPH Protein, E.coli (P. pastoris, His) is 341 a.a., with molecular weight of 40 kDa.

HY-P701773

	RSK2 Protein, Human RPS6KA3; Ribosomal Protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal Protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated Protein kinase 1; ISPK-1; MAP kinase-activated Protein kinase 1b; MAPK-activated Protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human is the recombinant human-derived RSK2 protein, expressed by E. coli , with tag free. The total length of RSK2 Protein, Human is 341 a.a., .

HY-P701774

	RSK2 Protein, Human (His) RPS6KA3; Ribosomal Protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal Protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated Protein kinase 1; ISPK-1; MAP kinase-activated Protein kinase 1b; MAPK-activated Protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; Ribosomal S6 kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human (His) is the recombinant human-derived RSK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RSK2 Protein, Human (His) is 341 a.a., .

HY-P72853

	BLK Protein, Human (sf9, GST) Tyrosine-Protein kinase Blk; B lymphocyte kinase; p55-Blk; BLK	Human	Sf9 insect cells
	The BLK protein is a key non-receptor tyrosine kinase that is essential for B lymphocyte development and signal transduction. It regulates pro-B to pre-B transition, growth arrest, and apoptosis downstream of B cell receptors by binding and phosphorylating CD79A and CD79B. BLK Protein, Human (sf9, GST) is the recombinant human-derived BLK protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of BLK Protein, Human (sf9, GST) is 505 a.a., with molecular weight of ~84 kDa.

HY-P702734

	GSK3B Protein, Human (sf9, GST) GSK3B; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 beta; GSK-3 beta; GSK3beta isoform; serine/threonine-Protein kinase GSK3B	Human	Sf9 insect cells

HY-P702650

	RPS6KA4 Protein, Human (sf9) RPS6KA4; ribosomal Protein S6 kinase, 90kDa, polypeptide 4; ribosomal Protein S6 kinase, 90kD, polypeptide 4; ribosomal Protein S6 kinase alpha-4; MSK2; RSK B; RSKB; S6K-alpha-4; ribosomal Protein kinase B; ribosomal Protein S6 kinase alpha 4; 90 kDa ribosomal Protein S6 kinase 4; mitogen- and stress-activated Protein kinase 2; nuclear mitogen- and stress-activated Protein kinase 2; RSK-B	Human	Sf9 insect cells

HY-P71549

	STK11 Protein, Human (His-SUMO) hLKB1; Liver kinase B1; LKB1; PJS; Polarization related Protein LKB1; Renal carcinoma antigen NY-REN-19; Serine/Threonine kinase 11; Serine/threonine Protein kinase 11; Serine/threonine Protein kinase LKB1; Serine/threonine Protein kinase STK11; Serine/threonine-Protein kinase 11; Serine/threonine-Protein kinase LKB1; Serine/threonine-Protein kinase XEEK1; Stk11; STK11_HUMAN	Human	E. coli
	The STK11 protein is a tumor suppressor kinase that complexly regulates members of the AMP-activated protein kinase (AMPK) family, affecting cellular processes such as metabolism, apoptosis, and DNA damage responses. It phosphorylates the T-loop of AMPK family proteins and activates PRKAA1, PRKAA2 and other proteins (except MELK). STK11 Protein, Human (His-SUMO) is the recombinant human-derived STK11 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of STK11 Protein, Human (His-SUMO) is 430 a.a., with molecular weight (affected by relative charge) of ~72 KDa.

HY-P70037

	CDKN1B Protein, Human (His) rHuCyclin-dependent kinase inhibitor 1B/CDKN1B, His; Cyclin-Dependent kinase Inhibitor 1B; Cyclin-Dependent kinase Inhibitor p27; p27Kip1; CDKN1B; KIP1	Human	E. coli
	The CDKN1B protein is a key cell cycle regulator that inhibits CDK2 when bound to cyclin A, thereby inhibiting G1 phase progression. It exhibits significant inhibitory effects on cyclin E- and cyclin A-CDK2 complexes. CDKN1B Protein, Human (His) is the recombinant human-derived CDKN1B protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDKN1B Protein, Human (His) is 198 a.a., with molecular weight of ~30.0 kDa.

HY-P701647

	TSSK1 Protein, Human (Sf9, GST) TSSK1B; Testis-specific serine/threonine-Protein kinase 1; TSK-1; TSK1; TSSK-1; Testis-specific kinase 1; Serine/threonine-Protein kinase 22A	Human	Sf9 insect cells
	The TSSK1 protein is a testis-specific serine/threonine protein kinase that plays a crucial role during late spermatogenesis, especially during cytoplasmic remodeling. It phosphorylates "Ser-288" of TSKS, which contributes to the transition of the ring structure around the base of the flagellum. TSSK1 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TSSK1 Protein, Human (Sf9, GST) is 366 a.a., .

HY-P701716

	BRSK1 Protein, Human (Sf9, GST) BRSK1; Serine/threonine-Protein kinase BRSK1; Brain-selective kinase 1; Brain-specific serine/threonine-Protein kinase 1; BR serine/threonine-Protein kinase 1; Serine/threonine-Protein kinase SAD-B; Synapses of Amphids Defective homolog 1; SAD1 homolog; hSAD1	Human	Sf9 insect cells
	The BRSK1 protein is a critical serine/threonine protein kinase that regulates cortical neuronal polarization and centrosome duplication. BRSK1 is phosphorylated and activated by STK11/LKB1, affecting neuronal polarization through MAPT/TAU phosphorylation (“Thr-529” and “Ser-579”) and WEE1 phosphorylation (“Ser-642”). BRSK1 Protein, Human (Sf9, GST) is the recombinant human-derived BRSK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of BRSK1 Protein, Human (Sf9, GST) is 777 a.a., .

HY-P701649

	TSSK2 Protein, Human (Sf9, GST) TSSK2; Testis-specific serine/threonine-Protein kinase 2; TSK-2; TSK2; TSSK-2; Testis-specific kinase 2; DiGeorge syndrome Protein G; DGS-G; Serine/threonine-Protein kinase 22B	Human	Sf9 insect cells
	The TSSK2 protein is a testis-specific serine/threonine protein kinase that is indispensable during late spermatogenesis and contributes to cytoplasmic remodeling. It is regulated by phosphorylating “Ser-288” of TSKS and SPAG16. TSSK2 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TSSK2 Protein, Human (Sf9, GST) is 357 a.a., .

HY-P71234

	PRKG1 Protein, Human (HEK293, His) cGMP-Dependent Protein kinase 1; cGK 1; cGK1; cGMP-Dependent Protein kinase I; cGKI; PRKG1; PRKG1B; PRKGR1A; PRKGR1B	Human	HEK293
	PRKG1, a serine/threonine protein kinase, mediates the NO/csignaling pathway, phosphorylating various cellular proteins. It influences platelet activation, smooth muscle contraction, cardiac function, CNS processes, and more. PRKG1 regulates intracellular calcium levels, inhibits IP3-induced Ca(2+) release, and phosphorylates channels like KCNMA1 and TRPC. It inactivates RhoA, affecting processes like vesicle trafficking and myosin light chain phosphorylation for vasorelaxation. NO-induced PRKG1 activation also alters gene expression, influencing smooth muscle-specific proteins and limiting smooth muscle cell migration. Additionally, it regulates VASP functions in platelets and smooth muscle. PRKG1 Protein, Human (HEK293, His) is the recombinant human-derived PRKG1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PRKG1 Protein, Human (HEK293, His) is 685 a.a., with molecular weight of ~75.0 kDa.

HY-P700583

	JAK1 Protein, Human (P. pastoris, His) JAK1; JAK1A; JAK1B; Tyrosine-Protein kinase JAK1; Janus kinase 1; JAK-1	Human	P. pastoris
	JAK1 protein is a non-receptor tyrosine kinase that plays a crucial role in IFN-α/β/γ signaling and serves as a kinase partner for IL-2 and IL-10 receptors. It cooperates with the type I interferon receptor IFNAR2 to phosphorylate and activate IFNAR2 upon interferon binding to IFNAR1-IFNAR2. JAK1 Protein, Human (P. pastoris, His) is the recombinant human-derived JAK1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of JAK1 Protein, Human (P. pastoris, His) is 305 a.a., with molecular weight of 36.9 kDa.

HY-P72048

	BTK Protein, Human (Baculovirus, His) Agammaglobulinaemia tyrosine kinase; AGMX 1; AGMX1; AT; ATK; B cell progenitor kinase; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton Tyrosine kinase; Btk; BTK_HUMAN; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD 1; IMD1; MGC126261; MGC126262; OTTHUMP00000063593; PSCTK 1; PSCTK1; truncated Bruton agammaglobulinemia tyrosine kinase; Tyrosine Protein kinase BTK; Tyrosine-Protein kinase BTK; tyrosine-Protein kinase BTK isoform lacking exon 14; XLA	Human	Sf9 insect cells
	The BTK protein is a key non-receptor tyrosine kinase that is essential for B lymphocyte development and signaling. After BCR activation, BTK initiates a cascade reaction, phosphorylates PLCG2 and activates downstream pathways, affecting calcium mobilization and PKC activation. BTK Protein, Human (Baculovirus, His) is the recombinant human-derived BTK protein, expressed by Sf9 insect cells , with N-10*His labeled tag. The total length of BTK Protein, Human (Baculovirus, His) is 659 a.a., with molecular weight of ~78.3 kDa.

HY-P700591

	GSK-3 beta Protein, Human (P. pastoris, His) Serine/threonine-Protein kinase GSK3B	Human	P. pastoris
	GSK-3 beta is an active protein kinase that regulates a variety of cellular processes. It negatively regulates glucose homeostasis, Wnt signaling, and transcription factors by phosphorylating substrates such as glycogen synthase, CTNNB1, and JUN. GSK-3 beta Protein, Human (P. pastoris, His) is the recombinant human-derived GSK-3 beta protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of GSK-3 beta Protein, Human (P. pastoris, His) is 420 a.a., with molecular weight of 48.7 kDa.

HY-P701788

	IKKε Protein, Human (Sf9, GST) IKKε; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	Human	Sf9 insect cells
	IKKε protein is a serine/threonine kinase that coordinates the inflammatory response to viral infection by activating type I IFN, NF-kappa-B, and STAT signaling pathways. Upon activation of the viral RNA sensor, IKKε binds to DDX3X and phosphorylates IRF3, IRF7, and DDX3X, resulting in IRF3 nuclear translocation. IKKε Protein, Human (Sf9, GST) is the recombinant human-derived IKKε protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of IKKε Protein, Human (Sf9, GST) is 715 a.a., .

HY-P701756

	PNCK Protein, Human (Sf9, GST) PNCK; Calcium/calmodulin-dependent Protein kinase type 1B; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase	Human	Sf9 insect cells
	The PNCK protein is a calcium/calmodulin-dependent protein kinase and a key component of the calcium-triggered signaling cascade. In vitro, PNCK exhibits the ability to phosphorylate CREB1 and SYN1/synapsin I, emphasizing its involvement in regulating cellular processes associated with these substrates. PNCK Protein, Human (Sf9, GST) is the recombinant human-derived PNCK protein, expressed by Sf9 insect cells , with GST tagged. The total length of PNCK Protein, Human (Sf9, GST) is 342 a.a., .

HY-P701757

	PNCK Protein, Human (Sf9, His, GST) PNCK; Calcium/calmodulin-dependent Protein kinase type 1B; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase	Human	Sf9 insect cells
	The PNCK protein is a calcium/calmodulin-dependent protein kinase and a key component of the calcium-triggered signaling cascade. In vitro, PNCK exhibits the ability to phosphorylate CREB1 and SYN1/synapsin I, emphasizing its involvement in regulating cellular processes associated with these substrates. PNCK Protein, Human (Sf9, His, GST) is the recombinant human-derived PNCK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PNCK Protein, Human (Sf9, His, GST) is 342 a.a., .

HY-P70381

	EphB1 Protein, Human (HEK293, Fc) rHuEphrin type-B receptor 1/EphB1, Fc; Ephrin Type-B Receptor 1; ELK; EPH Tyrosine kinase 2; EPH-Like kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine kinase; NET; Tyrosine-Protein kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6	Human	HEK293
	The EphB1 protein is a receptor tyrosine kinase that promiscuously binds to the transmembrane ephrin-B ligand of adjacent cells, initiating bidirectional signaling. The forward signal originates from the receptor and the reverse signal originates from the ephrin ligand. EphB1 Protein, Human (HEK293, Fc) is the recombinant human-derived EphB1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphB1 Protein, Human (HEK293, Fc) is 523 a.a., with molecular weight of 85-100 kDa.

HY-P76326

	FAM20B Protein, Human (HEK293, Fc) Glycosaminoglycan xylosylkinase; Xylose kinase; KIAA0475	Human	HEK293
	The FAM20B protein plays a key role in regulating mature glycosaminoglycan (GAG) chains by catalyzing xylose 2-O-phosphorylation in the glycosaminoglycan-protein linking region of the proteoglycan. This process is critical for the synthesis of sulfated GAGs (such as heparan sulfate and chondroitin sulfate) on the common GAG-protein linking region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of the core protein. FAM20B Protein, Human (HEK293, Fc) is the recombinant human-derived FAM20B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of FAM20B Protein, Human (HEK293, Fc) is 379 a.a., with molecular weight of ~75-80 KDa.

HY-P702710

	EphB2 Protein, Human (sf9, GST) EPHB2; EPH receptor B2; DRT, EphB2 , EPHT3, ERK; ephrin type-B receptor 2; Hek5; Tyro5; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; Protein-tyrosine kinase HEK5; tyrosine-Protein kinase TYRO5; renal carcinoma antigen NY-REN-47; tyrosine-Protein kinase receptor EPH-3; developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; ERK; CAPB; PCBC; EPHT3; MGC87492	Human	Sf9 insect cells

HY-P702639

	PRKCB Protein, Human (sf9, GST) PRKCB; Protein kinase C, beta; PKCB, PRKCB1, PRKCB2, Protein kinase C, beta 1; Protein kinase C beta type; PKC-B; Protein kinase C, beta 1 polypeptide; PKCB; PRKCB1; PRKCB2; PKC-beta; MGC41878	Human	Sf9 insect cells

HY-P701366

	CDK6-CCND1 Heterodimer Protein, Human (Sf9) CDK6; CCND1; Cyclin-dependent kinase 6; Cell division Protein kinase 6; Serine/threonine-Protein kinase PLSTIRE; G1/S-specific cyclin-D1; B-cell lymphoma 1 Protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene	Human	Sf9 insect cells
	The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6-CCND1 Heterodimer Protein, Human (Sf9) is a recombinant protein dimer complex containing human-derived CDK6-CCND1 Heterodimer protein, expressed by Sf9 insect cells , with tag free.

HY-P70793

	TrkB Protein, Human (HEK293, His) BDNF/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine kinase Receptor Type 2; TrkB Tyrosine kinase; Tropomyosin-Related kinase B; NTRK2; TRKB	Human	HEK293
	The TrkB protein is a key receptor tyrosine kinase that plays a key role in central and peripheral nervous system development. It regulates neuronal survival, proliferation, migration, differentiation, synapse formation, and plasticity. TrkB Protein, Human (HEK293, His) is the recombinant human-derived TrkB protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TrkB Protein, Human (HEK293, His) is 399 a.a., with molecular weight of 60-105 kDa.

HY-P702709

	EphB1 Protein, Human EPHB1; EPH receptor B1; EphB1 , EPHT2; ephrin type-B receptor 1; Hek6; EK6; EPH-like kinase 6; eph tyrosine kinase 2; soluble EPHB1 variant 1; tyrosine-Protein kinase receptor EPH-2; neuronally-expressed EPH-related tyrosine kinase; ELK; NET; EPHT2; FLJ37986	Human	E. coli

HY-P77449

	MOB4A/MOB1B Protein, Human (His) MOB kinase activator 1B; MOB4A; MOBKL1A; MOB1B	Human	E. coli
	In the Hippo signaling pathway, MOB4A/MOB1B, a crucial activator, controls organ size and suppresses tumors by regulating proliferation and promoting apoptosis. This pathway involves a kinase cascade where STK3/MST2 and STK4/MST1, with the regulatory protein SAV1, activate LATS1/2. In partnership with its regulator MOB1B, LATS1/2 phosphorylates and inactivates YAP1 and WWTR1/TAZ, influencing gene expression. MOB4A/MOB1B stimulates STK38L and interacts with LATS1 and LATS2, contributing to the complex regulatory network within the Hippo signaling pathway. MOB4A/MOB1B Protein, Human (His) is the recombinant human-derived MOB4A/MOB1B protein, expressed by E. coli, with N-6*His labeled tag. The total length of MOB4A/MOB1B Protein, Human (His) is 216 a.a., with molecular weight of 43-48 kDa.

HY-P70917

	MOB1A Protein, Human (His) MOB kinase Activator 1A; Mob1 Alpha; Mob1A; Mob1 Homolog 1B; Mps One Binder kinase Activator-like 1B; MOB1A; C2orf6; MOB4B; MOBK1B; MOBKL1B	Human	E. coli
	In the Hippo signaling pathway, MOB1A serves as a vital activator, governing organ size and suppressing tumors by modulating proliferation and apoptosis. Acting in a kinase cascade, MOB1A, along with STK3/MST2 and STK4/MST1, phosphorylates and activates LATS1/2, influencing the YAP1 oncoprotein and WWTR1/TAZ. This orchestrated phosphorylation controls gene expression pivotal for cell processes. Additionally, MOB1A stimulates STK38 and STK38L kinase activity, cooperating with STK3/MST2 and forming intricate interactions with key pathway components, contributing to its complex regulatory network. MOB1A Protein, Human (His) is the recombinant human-derived MOB1A protein, expressed by E. coli, with C-6*His labeled tag. The total length of MOB1A Protein, Human (His) is 215 a.a., with molecular weight of ~29.0 kDa.

HY-P702749

TAOK1 Protein, Human (sf9, His, GST)

TAOK1; TAO kinase 1; DDIB; PSK2; TAO1; KFC-B; MARKK; PSK-2; hKFC-B; hTAOK1; MAP3K16
Human Sf9 insect cells

HY-P700597

	PIP4K2B Protein, Human (His) PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; phosphatidylinositol 4 phosphate 5 kinase, type II, beta , PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PIP5KIIB; PIP5KIIbeta; PIP4KII-beta; PTDINS(4)P-5-kinase; PI(5)P 4-kinase type II beta; diphosphoinositide kinase 2-beta; ptdIns(5)P-4-kinase isoform 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; PI5P4KB; PIP5K2B	Human	E. coli
	PIP4K2B Protein actively synthesizes phosphatidylinositol 4,5-bisphosphate, preferring GTP over ATP in PI(5)P phosphorylation, with enzymatic activity linked to physiological GTP levels. Its unique GTP-sensing ability critically aids metabolic adaptation. PIP4K2B, part of PIP4Ks, negatively influences insulin signaling via a catalytic-independent mechanism, interacting with PIP5Ks to suppress PIP5K-mediated PtdIns(4,5)P2 synthesis, hindering insulin-dependent conversion to PtdIns(3,4,5)P3. This multifaceted role emphasizes PIP4K2B's significance in modulating key signaling pathways for cellular homeostasis and metabolic responsiveness. PIP4K2B Protein, Human (His) is the recombinant human-derived PIP4K2B protein, expressed by E. coli, with N-10*His labeled tag. The total length of PIP4K2B Protein, Human (His) is 415 a.a., with molecular weight of 53.3 kDa.

HY-P702633

	AKT3 Protein, Human (Active, sf9, GST) AKT3; AKT serine/threonine kinase 3; MPPH; PKBG; MPPH2; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma; RAC-gamma serine/threonine-Protein kinase; PKB gamma; RAC-gamma serine/threonine Protein kinase; v-akt murine thymoma viral oncogene homolog 3 (Protein kinase B, gamma); EC 2.7.11.1	Human	Sf9 insect cells

HY-P71206

	PIP4K2A Protein, Human (HEK293, His) 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PtdIns(4)P-5-kinase B isoform; PtdIns(4)P-5-kinase C isoform; PtdIns(5)P-4-kinase isoform 2-alpha	Human	HEK293
	The PIP4K2A protein phosphorylates phosphatidylinositol 5-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP4K2A Protein, Human (HEK293, His) is the recombinant human-derived PIP4K2A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PIP4K2A Protein, Human (HEK293, His) is 406 a.a., with molecular weight of 52-58 kDa.

HY-P702665

	PHKG1 Protein, Human (Active, sf9, GST) PHKG1; phosphorylase kinase, gamma 1 (muscle); phosphorylase kinase, gamma 1 (muscle); phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform; phosphorylase kinase gamma; phosphorylase kinase subunit gamma-1; EC 2.7.11.19	Human	Sf9 insect cells

HY-P75751

	EphB6 Protein, Human (HEK293) Ephrin type-B receptor 6; HEP; Tyrosine-Protein kinase-defective receptor EPH-6; EPHB6	Human	HEK293
	EphB6, a kinase-defective receptor, interacts with ephrin-B1 and ephrin-B2, regulating cell adhesion and migration. It inhibits JNK activation, reduces IL-2 secretion and CD25 expression in response to ephrin-B2. EphB6 interacts with CBL, EPHB1, and FYN, highlighting its multifaceted role in cellular signaling. EphB6 Protein, Human (HEK293) is the recombinant human-derived EphB6 protein, expressed by HEK293 , with tag free. The total length of EphB6 Protein, Human (HEK293) is 563 a.a., with molecular weight of ~72 kDa.

HY-P73090

	GSK-3 beta Protein, Mouse (sf9, His) Glycogen synthase kinase-3 beta; GSK-3 beta; Gsk3b	Mouse	Sf9 insect cells
	GSK-3 beta is a protein kinase that regulates cellular circadian rhythm, autophagy, and apoptosis. GSK-3 beta Protein, Mouse (sf9, His) is the recombinant mouse-derived GSK-3 beta protein, expressed by Sf9 insect cells , with N-10*His labeled tag. The total length of GSK-3 beta Protein, Mouse (sf9, His) is 420 a.a., with molecular weight of ~47 kDa.

HY-P74114

	GSK-3 beta Protein, Human (sf9, His) Glycogen synthase kinase-3 beta; GSK-3 beta; Gsk3b	Human	Sf9 insect cells
	The TrkA protein is a receptor protein that binds to the neurotrophin nerve growth factor (NGF). It plays a crucial role in the development and survival of neurons. GSK-3 beta Protein, Human (sf9, His) is the recombinant human-derived GSK-3 beta protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of GSK-3 beta Protein, Human (sf9, His) is 433 a.a., with molecular weight of 44-48 kDa.

HY-P75973

	PHKG1 Protein, Human (sf9, GST) Phosphorylase b kinase gamma catalytic chain; PHK-gamma-M; PHKG1; PHKG	Human	Sf9 insect cells
	PHKG1, the catalytic subunit of phosphorylase b kinase (PHK), plays a pivotal role in the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and activating glycogen phosphorylase. Beyond its involvement in glycogen metabolism, PHKG1 exhibits in vitro phosphorylation activity towards various substrates such as PYGM, TNNI3, MAPT/TAU, GAP43, and NRGN/RC3, indicating its potential role in diverse cellular processes. PHKG1 Protein, Human (sf9, GST) is the recombinant human-derived PHKG1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of PHKG1 Protein, Human (sf9, GST) is 387 a.a., with molecular weight of ~65 kDa.

HY-P702705

	TIE-2 Protein, Human (Biotinylated, sf9) TEK; TEK tyrosine kinase, endothelial; venous malformations, multiple cutaneous and mucosal , VMCM; angiopoietin-1 receptor; CD202b; TIE 2; TIE2; VMCM1; hTIE2; p140 TEK; soluble TIE2 variant 1; soluble TIE2 variant 2; endothelial tyrosine kinase; tyrosine-Protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-Protein kinase receptor TIE-2; tyrosine kinase with Ig and EGF homology domains-2; VMCM; TIE-2; CD202B	Human	Sf9 insect cells

Cat. No.	Product Name	Application	Reactivity

HY-P80788

Phospho-AKT1 (Ser473) Antibody AKT1; PKB; RAC; RAC-alpha serine/threonine-Protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	WB	Human, Mouse, Rat
Phospho-AKT1 (Ser473) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to Phospho-AKT (Ser473). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80789

Phospho-AKT (Thr308) Antibody AKT1; PKB; RAC; RAC-alpha serine/threonine-Protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
Phospho-AKT (Thr308) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 56 kDa, targeting to Phospho-AKT (Thr308). It can be used for ICC/IF,WB,IHC-F,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P80276

Phospho-AKT1(Ser473) Antibody AKT 1 antibody; AKT antibody; AKT1 antibody; AKT1_HUMAN antibody; MGC99656 antibody; PKB antibody; PKB-ALPHA antibody; PRKBA antibody; Protein kinase B Alpha antibody; Protein kinase B antibody; Proto-oncogene c-Akt antibody; RAC Alpha antibody; RAC antibody; RAC-alpha serine/threonine-Protein kinase antibody; RAC-PK-alpha antibody;	WB, ICC/IF, IHC-P	Human, Mouse
Phospho-Akt1(Ser473) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to Phospho-Akt1(Ser473). It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P80008

AKT1 Antibody (YA634) AKT 1; AKT; AKT1; AKT1_HUMAN ; MGC99656; PKB; PKB-ALPHA; PRKBA; Protein kinase B Alpha ; Proto-oncogene c-Akt; RAC Alpha;	WB, IHC-P, IP, FC	Human, Mouse
AKT1 Antibody (YA634) is a non-conjugated and Rabbit origined monoclonal antibody about 56 kDa, targeting to AKT1. It can be used for WB,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

HY-P83405

JNK3 Antibody (YA3150) Mitogen-activated Protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated Protein kinase 1b; SAPK1b; MAPK10; JNK3; JNK3A; PRKM10; SAPK1B	WB, ICC/IF, FC	Human, Mouse, Rat

HY-P83223

NME2 Antibody (YA2968) NME2; NM23B; Nucleoside diphosphate kinase B; NDK B; NDP kinase B; C-myc purine-binding transcription factor PUF; Histidine Protein kinase NDKB; nm23-H2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P80576

BTK Antibody (YA816) BTK; AGMX1; ATK; BPK; Tyrosine-Protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase	WB, IP	Human
BTK Antibody (YA816) is a non-conjugated and Mouse origined monoclonal antibody about 76 kDa, targeting to BTK (5B12). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P83469

MEK3 Antibody (YA3214) AW212142; dual specificity mitogen activated Protein kinase kinase 3; Dual specificity mitogen activated Protein kinase kinase 6; Dual specificity mitogen-activated Protein kinase kinase 3; MAP kinase kinase 3; MAP kinase kinase 6; map2k3; MAP2K6; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; Mitogen activated Protein kinase kinase 3; Mitogen activated Protein kinase kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein kinase; mitogen activated; kinase 6 (MAP kinase kinase 6); Protein kinase; mitogen-activated; kinase 3; SAPK kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated Protein kinase kinase 2; Stress activated Protein kinase kinase 3; Stress-activated Protein kinase kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat

HY-P80819

Phospho-GSK3 (Tyr216/Tyr279) Antibody Serine/threonine-Protein kinase GSK3A; Serine/threonine-Protein kinase GSK3B	WB, IP	Mouse, Rat
Phospho-GSK3 (Tyr216/Tyr279) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 51 kDa, targeting to Phospho-GSK3 (Tyr216/Tyr279). It can be used for WB,IP assays with tag free, in the background of Mouse, Rat.

HY-P80562

Aurora B Antibody AURKB; AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; Aurora kinase B; Aurora 1; Aurora- and IPL1-like midbody-associated Protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-Protein kinase 12	WB, IP	Human
Aurora B Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 39 kDa, targeting to Aurora B. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80698

GSK3 beta Antibody (YA744) GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-Protein kinase GSK3B	WB, IHC-P, FC	Human, Mouse, Rat
GSK3 beta Antibody (YA744) is a non-conjugated and Mouse origined monoclonal antibody about 47 kDa, targeting to GSK3 beta. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P83132

Ephrin Receptor B3 Antibody (YA2877) EPHB3; ETK2; HEK2; TYRO6; Ephrin type-B receptor 3; EPH-like tyrosine kinase 2; EPH-like kinase 2; Embryonic kinase 2; EK2; hEK2; Tyrosine-Protein kinase TYRO6	WB, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P80910

TBK1 Antibody (YA040) TBK1; NAK; Serine/threonine-Protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1	WB	Human, Mouse, Rat, Hamster
TBK1 Antibody (YA040) is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to TBK1. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P80820

Phospho-GSK3 beta (Ser9) Antibody GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-Protein kinase GSK3B	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
Phospho-GSK3 beta (Ser9) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 47 kDa, targeting to Phospho-GSK3 beta (Ser9). It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80850

Phospho-RSK2 (Ser227) Antibody RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal Protein S6 kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal Protein S6 kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated Protein kinase 1; ISPK-1; MAP kinase-activated Protein kinase 1b; MAPK-activated	WB, IP	Human, Mouse, Rat
Phospho-RSK2 (Ser227) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-RSK2 (Ser227). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P80726

JAK1 Antibody (YA722) JAK1; JAK1A; JAK1B; Tyrosine-Protein kinase JAK1; Janus kinase 1; JAK-1	WB, ICC/IF, IP	Human, Rat
JAK1 Antibody (YA722) is a non-conjugated and Mouse origined monoclonal antibody about 133 kDa, targeting to JAK1 (8B8). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Rat.

HY-P82431

Ephrin Receptor B1 Antibody (YA2176) EPHB1; ELK; EPHT2; HEK6; NET; Ephrin type-B receptor 1; ELK; EPH tyrosine kinase 2; EPH-like kinase 6; EK6; hEK6; Neuronally-expressed EPH-related tyrosine kinase; NET; Tyrosine-Protein kinase receptor EPH-2	WB, IP	Human, Mouse, Rat

HY-P83147

Ephrin Receptor B4 Antibody (YA2892)

EPHB4; HTK; MYK1; TYRO11; Ephrin type-B receptor 4; Hepatoma transmembrane kinase; Tyrosine-Protein kinase TYRO11
WB, IHC-P Human, Mouse, Rat

HY-P80586

Casein Kinase 2 beta Antibody CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
Casein Kinase 2 beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to Casein Kinase 2 beta. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80728

JNK Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, IP	Human, Mouse, Rat, Hamster
JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P80454

Phospho-BTK(Y223) Antibody BTK(Y223); BTK (phospho Y223); p-BTK (phospho Y223); Agammaglobulinaemia tyrosine kinase; AGMX 1; AGMX1; AT; ATK; B cell progenitor kinase; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton’s Tyrosine kinase; Btk; BTK_HUMAN; IMD 1; IMD1; MGC126261; MGC126262; OTTHUMP00000063593; PSCTK 1; PSCTK1; Tyrosine Protein kinase BTK; Tyrosine-Protein kinase BTK; XLA.	WB, IHC-P, IHC-F, ICC, IF	Human
Phospho-BTK(Y223) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 76 kDa, targeting to Phospho-BTK(Y223). It can be used for WB, IHC-P, IHC-F, ICC, IF assays with tag free, in the background of Human.

HY-P80445

CaMKII alpha Antibody 1 Publications Verification Alpha CaMKII; Calcium calmodulin dependent Protein kinase II; Calcium/calmodulin dependent Protein kinase II alpha B subunit; Calcium/calmodulin dependent Protein kinase type II alpha chain; Calcium/calmodulin-dependent Protein kinase (CaM kinase) II alpha; Calcium/calmodulin-dependent Protein kinase II alpha; Calcium/calmodulin-dependent Protein kinase II-alpha; Calcium/calmodulin-dependent Protein kinase type II subunit alpha; Calcium/calmodulin-dependent Protein kinase type IIA; CaM kinase II alpha chain; CaM kinase II alpha subunit; CaM kinase II subunit alpha; CaMK II alpha subunit; CaMK-II subunit alpha; Camk2a; CAMKA; CaMKII; CaMKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;	WB, IP, FC, IHC-P	Human, Mouse, Rat
CaMKII alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 54 kDa, targeting to CaMKII alpha. It can be used for WB,IP,FC,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80729

JNK1 Antibody (YA720) AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, ICC/IF	Human, Mouse, Rat
JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80877

PYK2 Antibody (YA682) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
PYK2 Antibody (YA682) is a non-conjugated and Mouse origined monoclonal antibody about 116 kDa, targeting to PYK2 (4B4). It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P83012

BUBR1 Antibody (YA2757) BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-Protein kinase BUB1 beta; MAD3/BUB1-related Protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1	WB, ICC/IF, IP	Human

HY-P80831

Phospho-JNK1 (Thr183/Tyr185) Antibody AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated Protein kinase 8; Mitogen-activated Protein kinase 8	WB, IP	Human, Rat
Phospho-JNK1 (Thr183/Tyr185) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to Phospho-JNK1 (Thr183/Tyr185). It can be used for WB,IP assays with tag free, in the background of Human, Rat.

HY-P81769

S6K2 Antibody (YA1514) RPS6KB2; STK14B; Ribosomal Protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal Protein S6 kinase 2; P70S6K2; p70-S6K 2; S6 kinase-related kinase; SRK; Serine/threonine-Protein kinase 14B; p70 ribosomal S6 kinase beta; S6K-beta; p70	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat

HY-P82145

Phospho-S6K2 (Ser371) Antibody (YA1890) RPS6KB2; STK14B; Ribosomal Protein S6 kinase beta-2; S6K-beta-2; S6K2; 70 kDa ribosomal Protein S6 kinase 2; P70S6K2; p70-S6K 2; S6 kinase-related kinase; SRK; Serine/threonine-Protein kinase 14B; p70 ribosomal S6 kinase beta; S6K-beta; p70	WB	Human, Mouse, Rat

HY-P80572

BRAF Antibody BRAF; BRAF1; RAFB1; Serine/threonine-Protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1	WB	Human, Mouse, Rat
BRAF Antibody is a non-conjugated and Mouse origined monoclonal antibody about 84 kDa, targeting to BRAF (4E1). It can be used for WB assays with tag free, in the background of Human, Mouse.

HY-P82244

Activin A Receptor Type IB Antibody (YA1989) ACVR1B; ACVRLK4; ALK4; Activin receptor type-1B; Activin receptor type IB; ACTR-IB; Activin receptor-like kinase 4; ALK-4; Serine/threonine-Protein kinase receptor R2; SKR2	WB	Human, Mouse, Rat

HY-P82712

ALK-1 Antibody (YA2457) ACVRL1; ACVRLK1; ALK1; Serine/threonine-Protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I	WB	Human, Mouse, Rat

HY-P80794

Phospho-BRAF (Thr401) Antibody BRAF; BRAF1; RAFB1; Serine/threonine-Protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1	WB, IP	Human, Mouse, Rat
Phospho-BRAF (Thr401) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-BRAF (Thr401). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P82599

CaMKII beta Antibody (YA2344) CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent Protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent Protein kinase type II subunit gamma	WB	Mouse

HY-P81209

RPS6KB1 Antibody p70(S6K)-alpha; ribosomal Protein S6 kinase; p70 S6 kinase; P70 Beta1; KS6B1_HUMAN; Ribosomal Protein S6 kinase beta-1; 70 kDa ribosomal Protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal Protein S6 kinase I; Serine/threonine-Protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA; S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha.	WB; ELISA; IHC-P; IHC-F; IF	Human, Rat(predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Goat)
RPS6KB1 Antibody is an unconjugated, approximately 70 kDa, rabbit-derived, anti-RPS6KB1 polyclonal antibody. RPS6KB1 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, rat, and predicted: mouse, chicken, dog, pig, cow, horse, rabbit, goat background without labeling.

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